Pillar 2: Serious, Data-Rich Medicine
We use advanced diagnostics and targeted therapies when they change decisions and outcomes—not as toys or upsells. Data from labs, imaging, wearables, and history feed one coherent plan for each member, led by physicians who have time to think.
Science & Evidence
This is the detail behind Pillar 2 — Serious, Data-Rich Medicine.
Evidence-informed medicine means grounding our approach in peer-reviewed research, not trends. If you like to see the papers behind the protocols, here are some of the studies that guide our work.
Epigenetics & Biological Age
Finding: DNA methylation patterns can accurately measure biological age, independent of chronological age.
What this means: We track your epigenetic age 2× per year to measure whether interventions are working.
Horvath, Genome Biology 2013 • Levine et al., Aging 2018
Preventive Biomarkers
Finding: Advanced lipid panels, inflammatory markers, and metabolic indicators predict disease risk years before symptoms.
What this means: Comprehensive diagnostics catch risk early—when intervention is most effective.
Ridker et al., NEJM 2017 • Emerging Risk Factors Collaboration, Lancet 2010
Lifestyle Medicine
Finding: Sustained behavior change in diet, movement, sleep, and stress resilience can add 10+ years of healthy life.
What this means: Foundations aren't just nice to have—they're the highest-ROI longevity intervention.
Li et al., Circulation 2018 • Khaw et al., PLoS Medicine 2008
Precision Medicine
Finding: Genomic and epigenomic data enable targeted interventions based on individual risk profiles.
What this means: Your plan is informed by your unique biology, not population averages.
Ashley, Nature Reviews Genetics 2016 • Precision Medicine Initiative, NIH 2015
Note: We stay current with longevity research and adjust protocols as evidence evolves. Not all interventions work for everyone; clinical judgment and individual context guide our recommendations.